UCL, UCLH and Formula One develop life-saving breathing aids for the NHS

‘Project Pitlane’ is a collective of UK-based Formula 1 teams and their respective technology arms coordinating a response to the UK government’s call for assistance with the manufacture of medical devices. It will pool the resources and capabilities of its member teams, focusing on the core skills of the F1 industry: rapid design, prototype manufacture, test and skilled assembly. F1’s ability to respond rapidly to engineering and technological challenges allows the group to add value to the wider engineering industry’s response.

The breathing aid, known as Continuous Positive Airway Pressure (CPAP), has been used extensively in hospitals in Italy and China to help Covid-19 patients with serious lung infections to breathe more easily when oxygen alone is insufficient.

Since Wednesday 18th March, engineers at UCL and HPP and clinicians at UCLH have been working round the clock at UCL’s engineering hub MechSpace to reverse engineer a device that can be produced rapidly by the thousands. This has now been recommended for use by the Medicines and Healthcare products Regulatory Agency (MHRA).

Professor Rebecca Shipley (UCL Mechanical Engineering) and Professor Mervyn Singer (UCL Medicine), who helped develop the device. Photographer: James Tye / UCL

This breathing aid was produced within a rapid timeframe – it took fewer than 100 hours from the initial meeting to production of the first device. One hundred devices are to be delivered to UCLH for clinical trials, with rapid roll-out to hospitals around the country ahead of the predicted surge in Covid-19 hospital admissions.

The collaboration, supported by the National Institute for Health Research UCLH Biomedical Research Centre, demonstrates the way that universities, the NHS and industry are coming together to help the national response to the Covid-19 coronavirus outbreak, by providing vital technologies to the NHS which can enable them to care for patients who require respiratory support.

Reports from Italy indicate that approximately 50% of patients given CPAP have avoided the need for invasive mechanical ventilation. However, such devices are in short supply in UK hospitals.

UCLH critical care consultant Professor Mervyn Singer (UCL Medicine) said: “These devices will help to save lives by ensuring that ventilators, a limited resource, are used only for the most severely ill.

A newly developed CPAP device. Photographer: James Tye / UCL.

“While they will be tested at UCLH first, we hope they will make a real difference to hospitals across the UK by reducing demand on intensive care staff and beds, as well as helping patients recover without the need for more invasive ventilation.”

Professor Rebecca Shipley, Director of UCL Institute of Healthcare Engineering, said: “At UCL, we have an established ecosystem of partnerships spanning engineers, healthcare and industry ready to be mobilised in times of need. It’s been a privilege to work closely with our clinical colleagues and with doctors leading the Covid-19 response in China and Italy. This close contact has helped us to define the need and respond with technology that we hope will support the NHS in the weeks and months to come.”

Professor Tim Baker (UCL Mechanical Engineering) said: “Given the urgent need, we are thankful that we were able to reduce a process that could take years down to a matter of days.

A volunteer ‘patient’ with the newly developed CPAP device. Photographer: James Tye / UCL

“From being given the brief, we worked all hours of the day, disassembling and analysing an off-patent device. Using computer simulations, we improved the device further to create a state-of-the-art version suited to mass production.

“We were privileged to be able to call on the capability of Formula One – a collaboration made possible by the close links between UCL Mechanical Engineering and HPP.”




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